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Ivonescimab in combination with chemotherapy in advanced or metastatic gastric cancer (GC) or esophagogastric junction cancer (EGJC): The UCGI 52 - GRACIE trial.

Judith Raimbourg, Damien Botsen, Simon Pernot, Valérie Boige, Mélanie Dos Santos, Clélia Coutzac, Nicolas De Sousa Carvalho, Cristina Smolenschi, Christelle de la Fouchardière

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the LiverOct 1, 2026PMID 42669571doi:10.1016/j.dld.2026.08.003 Journal ArticleMulticenter StudyClinical Trial, Phase IIpubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
Published

Abstract

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BACKGROUND: While the addition of Ivonescimab to chemotherapy has demonstrated promising results in non-small cell lung cancer compared with chemotherapy alone, its efficacy as a first- or second-line treatment in advanced/metastatic gastric cancer remains to be established. AIMS: GRACIE aims to…

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Validated 1

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Registered trialsNCT06846346

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