Publication
Imaging-guided COX-2 inhibition synergizes with photodynamic immunogenic cell death to potentiate checkpoint blockade in colon cancer.
Lina Wu, Xijun Chen, Jiaoling He, Xiaoliang Deng, Shiying Xu, Boxin Chen, Chen Zheng, Xianquan Feng, Yan Zhang
International journal of pharmaceutics: XDec 1, 2026PMID 42668486doi:10.1016/j.ijpx.2026.100642 PMC13524588Journal ArticlepubmedProvenance
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- PubMed
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- Sep 17, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260917-000001
Abstract
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Colon cancer is a highly aggressive malignancy lacking specific therapeutic targets. Here, we present a therapeutic strategy that integrates inflammation-driven nanomedicine-based photodynamic therapy (PDT) with immune checkpoint blockade (ICB), with holds the potential to eradicate primary tumors…
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Candidate 1
- cancerMalignant Colon Neoplasmdictionary0.60
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