Publication
TRIB3 promotes triple-negative breast cancer metastasis by restricting lipophagy through the PI3K/AKT/mTOR signaling pathway.
Liqiong Ruan, Jianfeng Liu, Zirong Jiang
Cellular signallingDec 1, 2026PMID 42668127doi:10.1016/j.cellsig.2026.112852 Journal ArticlepubmedProvenance
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- Sep 28, 2026
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- ING-PUBMED-20260928-000001
Abstract
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BACKGROUND: Lipophagy-driven metabolic reprogramming is increasingly recognized as a determinant of tumor progression. TRIB3, a key regulator of lipid metabolism, has been implicated in cancer aggressiveness, with elevated expression linked to poor outcomes in triple-negative breast cancer. Here,…
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- cancerMalignant Breast Neoplasmdictionary0.60
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