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Role of estrogen receptor α in the regulation of breast cancer progression: signaling pathways and therapeutic implications.

Betty Annie Samuel, Selvaraj Jubie, Natarajan Jawahar, Pk Krishnan Namboori, Anil K Philip

GeneDec 5, 2026PMID 42665030doi:10.1016/j.gene.2026.150376 Journal ArticleReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 26, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260926-000001
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Estrogen receptor alpha (ERα) is central to breast-cancer initiation, progression, and endocrine resistance. This narrative review uses a transparent, non-systematic search of peer-reviewed English-language literature published from 2017 through 2025 to integrate ERα structure and isoforms, genomic…

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