Publication
RET-driven osteoprotegerin expression links medullary thyroid cancer to osteoblastic bone metastases.
Rozita Bagheri-Yarmand, Gabriel M Pagnotti, Joseph L Kidd, David Avila Ramirez, Trupti Trivedi, Leah Guerra, Zhongya Wang, Lucia Martinez Cruz, Jade M Moehle, Yaashmin S Jebaraj, Xinhai Wan, Jian H Song, Roland L Bassett, Sue-Hwa Lin, Mimi I Hu, Steven I Sherman, Marie-Claude Hofmann, Theresa A Guise
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- PubMed
- Retrieved
- Sep 26, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260926-000001
Abstract
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Development of bone metastases increases mortality in patients with medullary thyroid cancer (MTC), with ∼50% survival at 5 years after diagnosis, but the underlying mechanisms of action are unknown. We show that patient-derived MTC cells (RETC634W mutant TT and RETM918T mutant MZCRC1 cells)…
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Candidate 1
- cancerMalignant Thyroid Gland Neoplasmdictionary0.60
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