Publication
A glucose metabolism-targeted nanoplatform amplifies disulfidptosis-associated immunogenic cell death in triple-negative breast cancer.
Jialin Xu, Yanting Sun, Bin Huang, Yifan Zhang, Hongyu Shen, Zhengxing Zhou, Min Tian, Tianyu Zeng, Shuai Wu, Yongmei Yin
Redox biologyOct 1, 2026PMID 42660058doi:10.1016/j.redox.2026.104358 PMC13544341Journal ArticlepubmedProvenance
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- PubMed
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- Sep 19, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260919-000001
Abstract
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Disulfidptosis is a metabolism-dependent form of cell death driven by disulfide stress that induces actin cytoskeletal collapse in SLC7A11-high cells under glucose deprivation. However, strategies to therapeutically exploit this vulnerability remain underdeveloped. Given the high dependence of…
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- cancerMalignant Breast Neoplasmdictionary0.60
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