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Oncotype DX-guided vs physician-directed chemotherapy and survival in HR+/HER2- breast cancer.

Jingkun Li, Xinhao Han, Yan Zhuang, Yinting Liu, Samantha M Thomas, Jennifer K Plichta, Jinsong Wang, Bo Lei

Breast (Edinburgh, Scotland)Oct 1, 2026PMID 42659874doi:10.1016/j.breast.2026.104906 PMC13545399Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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BACKGROUND: Oncotype DX testing guides adjuvant chemotherapy decisions in early-stage hormone receptor-positive/HER2-negative breast cancer, but testing is not universally performed, and outcomes associated with genomic-informed versus clinicopathologic-based chemotherapy decision pathways remain…

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