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Refined Continuous Risk Index for Accurately Predicting Outcomes of Patients With Chronic Lymphocytic Leukemia After Limited-Duration Therapy.

Othman Al-Sawaf, Can Zhang, Mohammad S Esfahani, Chih Long Liu, Sandra Robrecht, Eugen Tausch, Anke Schilhabel, Matthias Ritgen, Christof Schneider, Martin Peifer, Moritz Fürstenau, Carsten Utoft Niemann, Arnon P Kater, John F Seymour, Brenda Chyla, Yanwen Jiang, Barbara Eichhorst, Stephan Stilgenbauer, Michael Hallek, Ash A Alizadeh, David M Kurtz, Kirsten Fischer

Journal of clinical oncology : official journal of the American Society of Clinical OncologyOct 1, 2026PMID 42659576doi:10.1200/JCO-26-00161 PMC13623073Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261001-000001
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PURPOSE: Measurable residual disease (MRD) status after limited-duration treatment for chronic lymphocytic leukemia (CLL) strongly predicts survival times and is considered a surrogate end point. However, most prognostic indices, including the International Prognostic Index (CLL-IPI), rely solely…

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