Skip to content
CancerIndex

Publication

Dose-Response Relationships for Lung Tumor and Pleural Mesothelioma Induction by Repetitive Intratracheal Instillation of a Multiwalled Carbon Nanotube, MWCNT-7, in Rats: Comparison with Inhalation Carcinogenicity Based on Lung Burden.

Ai Maeno, Motoki Hojo, Yoshimitsu Sakamoto, Yukio Yamamoto, Kiyomi Ikushima, Kai Igarashi, Satoshi Yokota, Yuhji Taquahashi, Norihiro Kobayashi, Hiroyuki Tsuda, Aya Naiki-Ito, Takamasa Numano, Jun Kanno, Akihiko Hirose, Akiko Inomata, Junichi Kamiie, Dai Nakae

Nanomaterials (Basel, Switzerland)Aug 20, 2026PMID 42646448doi:10.3390/nano16161039 PMC13515796Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260908-000002
Published

Abstract

Abstract (excerpt)

Only the opening of the abstract is shown; abstract text may carry publisher copyright.

The multiwalled carbon nanotube, MWCNT-7, is carcinogenic to rat lungs when inhaled over the course of 2 years, but does not induce pleural mesothelioma. In contrast, intratracheal instillation of MWCNT-7 causes both lung tumors and pleural mesotheliomas. To explore the possibility of the use of…

Read on PubMed

Linked entities

Linked entities (1)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Candidate 1

Curated evidence

Evidence citing this paper (0)

Data not yet available

No curated evidence item cites this publication.