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Suppressed cGAS-STING DNA Sensing Drives Immune Evasion in Anaplastic Thyroid Cancer.

Xu-Guang Zhu, Manju Acharya, Eunmi Hwang, Nathan Wong, Naris Nilubol, Sheue-Yann Cheng

Thyroid : official journal of the American Thyroid AssociationOct 1, 2026PMID 42644464doi:10.1177/10507256261481666 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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BACKGROUND: Anaplastic thyroid cancer (ATC) is a highly lethal malignancy with poor survival and limited therapeutic options. The mechanisms driving immune evasion in ATC remain poorly understood. The cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway is a key mediator of…

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