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Treatment outcomes in patients with p16-negative oropharyngeal cancer: a comparison of initial surgery and definitive chemoradiotherapy.

Younghac Kim, Taek Yoon Cheong, Sang Hoo Park, Man Ki Chung, Han-Sin Jeong, Young-Ik Son, Nayeon Choi

Acta oto-laryngologicaAug 26, 2026PMID 42644397doi:10.1080/00016489.2026.2719394 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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BACKGROUND: p16-negative oropharyngeal squamous cell carcinoma (OPSCC) has a poorer prognosis than p16-positive disease, but evidence on optimal treatment and salvage-related morbidity remains limited. AIMS AND OBJECTIVES: To compare outcomes of initial surgery-based treatment and definitive…

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