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Co-treatment with pyrvinium pamoate and hispidulin potently reduces stemness and promotes mitochondrial apoptosis in prostate cancer cells.

Riza Serttas, Suat Erdogan

CytotechnologyOct 1, 2026PMID 42643730doi:10.1007/s10616-026-01056-x PMC13504029Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260919-000001
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Pyrvinium pamoate, originally developed for protozoal infections, has emerged as a small-molecule inhibitor that interferes with Wnt/β-catenin signaling by suppressing β-catenin stability and downstream target gene activation. Wnt/β-catenin signaling pathway is a key intracellular regulatory…

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