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Single-cell chromatin profiling reveals relapse-related priming in pediatric acute myeloid leukemia.

Boyu Cui, Minghui Lei, Liwei Liu, Mingxin Shu, Furong Yu, Kai Yang, Yin Pan, Yunhong Song

Life science allianceNov 1, 2026PMID 42637517doi:10.26508/lsa.202603746 PMC13504080Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
Published

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Relapse remains the leading cause of treatment failure and mortality in pediatric acute myeloid leukemia (pAML), yet the early molecular features underlying relapse susceptibility remain poorly understood. Here, we leveraged our previously generated single-cell chromatin accessibility dataset…

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