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Acid-activated Fe-doped layered double hydroxides coupling FAK blockade and chemodynamic therapy for triple-negative breast cancer.

Xiaokang Gao, Qiang Zhang, Hui Xu, Yuchen Gu, Qige Xia, Qiwang Zhou, Jie Bian

Biomaterials advancesDec 1, 2026PMID 42636671doi:10.1016/j.bioadv.2026.215110 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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Triple-negative breast cancer (TNBC) remains a highly aggressive malignancy with limited therapeutic targets and frequent treatment resistance. Focal adhesion kinase (FAK), encoded by PTK2, regulates tumor-cell survival and motility, but the efficacy of small-molecule FAK inhibitors is limited by…

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