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Proteomic profiling reveals that DPP4 overexpression increases cell adhesion, inhibits cell migration, and restores androgen sensitivity in prostate cancer.

José María Mora-Rodríguez, Belén G Sánchez, Alicia Bort, Alba Díaz-Yuste, Alicia Milla, Julie Courraud, Jerome Zoidakis, Inés Díaz-Laviada

Bioscience reportsSep 16, 2026PMID 42634954doi:10.1042/BSR20260054 PMC13542909Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 17, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260917-000001
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Dipeptidyl peptidase-4 (DPP4), a serine protease with both enzymatic and non-enzymatic roles, has emerged as a context-dependent modulator of tumor progression. In the present study, we investigated the expression and function of DPP4 in androgen-sensitive and castration-resistant prostate cancer…

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