Publication
Short and efficient synthesis of the natural triterpenoids α- and β-amyrins with detailed in silico screening and in vitro anticancer evaluation against breast and prostate cancer cells.
Halil Şenol, Salih Tuncay, Şeyma Ateşoğlu, Abdullah Menzek, Hasan Seçen, Gülaçtı Topçu
Computational biology and chemistryDec 1, 2026PMID 42632245doi:10.1016/j.compbiolchem.2026.109333 Journal ArticlepubmedProvenance
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- PubMed
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- Sep 17, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260917-000001
Abstract
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α- and β-Amyrins are biologically important pentacyclic triterpenoids that occur at low levels in natural sources, making their isolation difficult. In this study, a simple and cost-effective semisynthetic route was developed to obtain α- and β-amyrins from ursolic acid and oleanolic acid in three…
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- cancerMalignant Prostate Neoplasmdictionary0.60
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