Publication
Green synthesis of N-aryl-1-(2-bromo-4-methyl phenyl)-1H-tetrazol-5-amines as novel anti-cancer agents targeting tubulin-Combretastatin A4 complex and human non-small cell lung cancer cell lines.
Uma Ravi Sankar Arigala, Raju Vasantham, Santhosh Kumar Nadikatla, Ibrahim Khalivulla Shaik, Yellappa Masapogu
Bioorganic chemistryOct 5, 2026PMID 42632199doi:10.1016/j.bioorg.2026.110410 Journal ArticlepubmedProvenance
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- PubMed
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- Sep 19, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260919-000001
Abstract
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A series of N-aryl-1-(2-bromo-4-methyl phenyl)-1H-tetrazol-5-amines was synthesized through a two-step microwave-assisted protocol from 2-bromo-1-isothiocyanato-4-methylbenzene and substituted aryl amines. Initially, thiourea derivatives were prepared under solvent-free microwave conditions,…
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- cancerMalignant Lung Neoplasmdictionary0.60
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