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CD7 CAR-T cells eliminate chronic myeloid leukemia stem cells specifically and effectively.

Wenjing Zhang, Haobing Wang, Ling Tang, Yingjie Kong, Yong You, Xiaojian Zhu, Hongxiang Wang

Hematology (Amsterdam, Netherlands)Dec 31, 2026PMID 42629973doi:10.1080/16078454.2026.2719241 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
Published

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OBJECTIVES: Leukemia stem cells (LSCs) in chronic myeloid leukemia (CML) are associated with disease recurrence and progression, cannot be eliminated by tyrosine kinase inhibitors (TKIs), and affect TKI discontinuation in CML patients. Chimeric antigen receptor T cells (CAR-T) therapy can eliminate…

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