Publication
Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36.
Jade Alvarez, Pola Olczak, Hua-Ling Tsai, Jasmine Terrell, Margaret Wong, Hannah Tsingine, Vikrant Palande, Jeanette Prangsgaard, Emma Huus, Martin Műller, John Dirk Vestergaard Nieland, Richard B S Roden
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- PubMed
- Retrieved
- Sep 28, 2026
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- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260928-000001
Abstract
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A phase I study was conducted in 20 healthy subjects with 20 µg adeno-associated virus 2 (AAV2)-like particles displaying L2 residues 17-36 of both human papillomavirus (HPV) type 16 and HPV31 (AAVLP-HPV) or placebo. AAVLP-HPV vaccination was well tolerated and induced a modest L2-specific serum…
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- trialNCT03929172registry_reference1.00
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