Publication
Emergence of glycolysis-lactate-Lactylation Axis in breast cancer: Mechanisms, tumour progression, and therapeutic implications.
Ishika Tyagi, Sonali Sundram, Sathvik Belagodu Sridhar, Javedh Shareef, Tarun Wadhwa, Daniel Arockiam, Rishabha Malviya
Cellular signallingDec 1, 2026PMID 42624344doi:10.1016/j.cellsig.2026.112834 Journal ArticleReviewpubmedProvenance
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- PubMed
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- Sep 19, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260919-000001
Abstract
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Breast cancer is a uniquely metabolically reprogrammed cancer, with increased aerobic glycolysis, excess lactate production, and the development of an excess of lysine lactylation. This glycolysis-lactate-lactylation signal has become a key player in the control of tumour growth and resistance to…
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- cancerMalignant Breast Neoplasmdictionary0.60
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