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10,11-Dehydrocurvularin suppresses non-small cell lung cancer by targeting PAICS and inducing apoptosis.

Yue Wang, Siyu Chen, Ping Huang, Mewlude Rehmutulla, Yang Xiao, Yaxin Duan, Yang Fu, Xian Xia, Jiangchun Wei, Zhengxi Hu, Qingyi Tong, Yonghui Zhang

Bioorganic chemistryOct 5, 2026PMID 42623919doi:10.1016/j.bioorg.2026.110379 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 12, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260912-000001
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Non-small cell lung cancer (NSCLC) remains one of the leading causes of cancer-related mortality worldwide, highlighting the urgent need for effective therapeutic agents. Natural products represent an important source of novel anticancer compounds. In this study, we investigated the anti-NSCLC…

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