Publication
TIGIT-associated immune cell exhaustion in pediatric B-cell acute lymphoblastic leukemia: An integrated clinical and transcriptomic analysis.
Fatemah S Basingab
Clinical immunology (Orlando, Fla.)Oct 1, 2026PMID 42617963doi:10.1016/j.clim.2026.110763 Journal ArticlepubmedProvenance
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- Sep 18, 2026
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Immune checkpoint dysregulation contributes to cytotoxic lymphocyte exhaustion in hematologic malignancies. TIGIT, an inhibitory immune receptor expressed on activated T and natural killer (NK) cells, is a key regulator of immune exhaustion. However, its transcriptional landscape in pediatric acute…
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