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Patient-derived models of prostate cancer: Capturing tumour complexity from initiation to metastasis.

Clémentine Le Magnen, W Nathaniel Brennen, Álvaro Aytes, Nathalie Bock, Robert G Bristow, Nicholas Choo, Chee Wai Chua, Ashlee K Clark, Judith A Clements, Ilsa M Coleman, Eva Corey, Marija Dinevska, Dimitrios Doultsinos, Giselle Edge, Jeff Holst, Lisa G Horvath, Estefania Labanca, Stephen Lyons, María Victoria Luna-Velez, Wouter Karthaus, Marianna Kruithof-de Julio, Lisa K Philp, Gail S Prins, Weranja Ranasinghe, Luke A Selth, Peter Shepherd, Anna Taubenberger, Renea A Taylor, Paul Timpson, David J Waugh, Wytske M van Weerden, Gail P Risbridger, Mitchell G Lawrence

Cancer lettersOct 28, 2026PMID 42617726doi:10.1016/j.canlet.2026.218791 Journal ArticleReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 18, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260918-000001
Published

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Prostate cancer is a growing global health challenge. To identify new ways to improve patient care, researchers need a variety of preclinical models that faithfully recapitulate human tumours across the disease continuum, from initiation to metastasis. These complementary models include primary…

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