Publication
Attenuated Salmonella typhimurium VNP20009 L-forms suppress tumor growth and metastasis by inhibiting TGF-β1/Snail/Vimentin pathway in murine lung cancer.
Wei Zhao, Qin Chen, Cuiping Yang, Yifan Chu, Jiyu Yang, Junru Chen, Dengyu Chen
European journal of pharmacologyOct 15, 2026PMID 42612770doi:10.1016/j.ejphar.2026.179240 Journal ArticlepubmedProvenance
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- Sep 17, 2026
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- ING-PUBMED-20260917-000001
Abstract
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BACKGROUND: Attenuated Salmonella typhimurium (ST) VNP20009 exhibits tumor-targeting properties but limited therapeutic efficacy. Bacterial L-forms, which lack a cell wall, may offer enhanced antitumor activity. This study compared the efficacy of VNP20009 and its bacterial L-forms against murine…
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- cancerMalignant Lung Neoplasmdictionary0.60
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