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Targeted therapy of colon cancer with aptamer-functionalized albumin nanoparticles loaded with disulfiram.

Yacong An, Zhen Yu, Ting Li, Xundou Li, Qiping Jiang

NanotechnologySep 1, 2026PMID 42612683doi:10.1088/1361-6528/ae9b13 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 13, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260913-000001
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Chemotherapy remains the primary treatment for most patients with metastatic colorectal cancer (mCRC), yet its efficacy is often limited by severe adverse effects. Drug repurposing offers a promising strategy to accelerate oncology drug development. Disulfiram (DSF), a licensed anti-alcoholism…

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