Publication
Synthesis and biological evaluation of 68Ga-DOTA-PLE: a Plectin-1-targeted radiotracer for PET/MR imaging of pancreatic cancer.
Zhi-Qiang Yu, Hongrui Shu, Yujie Wang, Shun Li, Zhen-Peng Yu, Weijia Zhao, Xue-Feng Zhao, Hong Zhu, Yi Du, Pai Peng, Hongwei Si, Peng-Fei Dai
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- PubMed
- Retrieved
- Sep 13, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260913-000001
Abstract
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PURPOSE: Pancreatic cancer is characterized by high malignancy and diagnostic challenges. Plectin-1 is a specific biomarker significantly overexpressed in pancreatic ductal adenocarcinoma (PDAC). This study aimed to synthesize a Plectin-1-targeting radiotracer, 68Ga-DOTA-PLE, and evaluate its…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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