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ADRB2 modulates asbestos-induced pleural mesothelioma progression by influencing IL-17/NF-κB-related inflammatory signalling: An integrated network toxicology, multi-omics and experimental study.

Shaoyang Huang, Dandan Gu, Jintao He, Guangsheng Hou, Jundong Wang, Zhengliang Li, Min Yu, Jiangyan Li, Wei Xiong

Chemico-biological interactionsOct 1, 2026PMID 42595249doi:10.1016/j.cbi.2026.112302 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 12, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260912-000001
Published

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Pleural mesothelioma (PM) is a highly aggressive asbestos-related malignancy with a poor prognosis and limited early diagnostic options. In this study, network toxicology and integrated multi-omics analyses were used to investigate the molecular mechanisms by which chrysotile, crocidolite, and…

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