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A lipid droplet-targeted AIE photosensitizer for efficient multi-type ROS generation and breast cancer photodynamic therapy.

Yukun Zhang, Lidong Deng, Qiyan Li, Lie Li, Shining Li, Ruiyuan Liu, Jinqing Qu

Bioorganic chemistryOct 5, 2026PMID 42594420doi:10.1016/j.bioorg.2026.110376 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 11, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260911-000001
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Photodynamic therapy (PDT) is a promising non-invasive strategy for breast cancer, yet its clinical translation is hindered by fluorescence quenching, insufficient reactive oxygen species (ROS) generation and poor tumor targeting. Herein, a novel lipid droplet-targeted aggregation-induced emission…

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