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Disease-free survival as a surrogate outcome for localized kidney cancer-A systematic review and meta-analysis.

Constanza Martinez, David Chen, Russell Leong, Nicholas Lum, Karren Xiao, Laith Almasri, Christian K Kollmannsberger, Srinivas Raman

CancerAug 15, 2026PMID 42590929doi:10.1002/cncr.70567 PMC13469989Journal ArticleSystematic ReviewMeta-AnalysispubmedProvenance
Source
PubMed
Retrieved
Sep 13, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260913-000001
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BACKGROUND: Disease-free survival (DFS) is commonly used as a primary end point in trials for localized renal cell carcinoma (RCC), although its validity as a surrogate for overall survival (OS) remains uncertain. The objective of this study was to evaluate whether DFS is a reliable surrogate end…

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