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Alkyl-chain-length-associated responses of K562 leukemia cells to methyl-, ethyl-, and butylparaben with a focus on PPARγ and WNT/β-catenin signaling.

Konrad A Szychowski, Bartosz Skóra

Toxicology and applied pharmacologyOct 1, 2026PMID 42586446doi:10.1016/j.taap.2026.117994 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260908-000002
Published

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Parabens are antimicrobial preservatives with endocrine-disrupting potential. Because methylparaben (MeP), ethylparaben (EtP), and butylparaben (BuP) differ in alkyl-chain length and biological potency, their comparison may reveal structure-dependent cellular responses. Using K562 chronic myeloid…

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