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Efficacy, safety, and mitochondrial mechanisms of myricetin in a preclinical model of trastuzumab-resistant HER2+ breast cancer.

Yaqing Zhu, Wenjuan Yang, Gege Guan, Cuiling Zhou

Toxicology in vitro : an international journal published in association with BIBRADec 1, 2026PMID 42586176doi:10.1016/j.tiv.2026.106294 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 11, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260911-000001
Published

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Trastuzumab resistance remains a major clinical barrier in the treatment of HER2-positive breast cancer. To identify therapeutic candidates capable of overcoming resistance, we established trastuzumab-resistant derivatives of SKBR3 and BT474 cells and performed a high-throughput screen of a…

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