Publication
Deubiquitination of ME1 by OTUD7B promotes aerobic glycolysis of esophageal cancer.
Liyang Guan, Xin Li, Zaixing Du, Qianhui Yuan, Fuxin Zhou, Xiaotong Li, Jianfeng Xu, Zhecheng Wang, Mei Lv, Li Lv
Biochemical pharmacologyNov 1, 2026PMID 42580490doi:10.1016/j.bcp.2026.118340 Journal ArticlepubmedProvenance
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- Sep 10, 2026
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- ING-PUBMED-20260910-000001
Abstract
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Esophageal cancer (EC) is among the most prevalent malignancies worldwide. Malic enzyme 1 (ME1), which catalyzes the oxidative decarboxylation of malate to pyruvate, contributes to the Warburg effect (aerobic glycolysis) and plays a pivotal role in the progression of tumor growth. Nevertheless, the…
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- cancerMalignant Esophageal Neoplasmdictionary0.60
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