Publication
Keratan sulfate proteoglycans in pancreatic cancer: From stromal architects to potential therapeutic targets.
Wenjing Liang, Dongyi Lyu, Kunzheng Fan, Chao Liu, Qiang Ren, Huijie Gao, Yuntao Zhang
Biochimica et biophysica acta. Reviews on cancerOct 1, 2026PMID 42580456doi:10.1016/j.bbcan.2026.189682 Journal ArticleReviewpubmedProvenance
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- Oct 1, 2026
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Pancreatic cancer features a dense desmoplastic stroma that drives therapeutic resistance and immune evasion. Traditionally viewed as inert scaffolds, keratan sulfate proteoglycans (KSPGs) now emerge as active signaling modulators within this tumor microenvironment. This review elucidates the…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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