Publication
Pegaspargase Rechallenge Following Grade 2 Hypersensitivity Reaction in Childhood Acute Lymphoblastic Leukemia: Results of DFCI 16-001.
Melissa A Burns, Yael Flamand, Julia Keating, Victoria Koch, Sarah M Cronholm, Sarah K Hunt, Peter D Cole, Lisa M Gennarini, Nobuko Hijiya, Justine M Kahn, Kara M Kelly, Bruno Michon, Donna S Neuberg, Andrew E Place, Caroline Laverdière, Thai Hoa Tran, Yves Théorêt, Jennifer J G Welch, Stephen E Sallan, Lewis B Silverman, Lynda M Vrooman
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- PubMed
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- Sep 10, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260910-000001
Abstract
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Hypersensitivity reactions with pegylated Escherichia coli-derived asparaginase formulations are frequent and can complicate delivery of intended therapy for patients with acute lymphoblastic leukemia (ALL). On DFCI 16-001, which enrolled patients aged 1-21 years with newly diagnosed ALL, we…
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- cancerLeukemiadictionary0.60
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