Publication
Structure-based screening and identification of a novel Aurora-A-targeting peptide with antiproliferative activity against prostate cancer cells.
Bei-Bei Huang, Haijing Jiang, Yaozhi Hu, Jia-Jia Ge, Xiaohao Liu
Journal of enzyme inhibition and medicinal chemistryDec 1, 2026PMID 42578512doi:10.1080/14756366.2026.2700842 PMC13463526Journal ArticlepubmedProvenance
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- PubMed
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- Sep 10, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260910-000001
Abstract
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Aurora-A is a potential therapeutic target in prostate cancer. In this study, virtual screening identified four Aurora-A-targeting peptides, among which Peptide-1 showed the most favourable profile. Molecular docking and MST assays demonstrated that Peptide-1 had the lowest predicted binding free…
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Candidate 1
- cancerMalignant Prostate Neoplasmdictionary0.60
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