Publication
Low Dasatinib Penetration of the Blood-Brain Barrier in Children With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Evidence From LC-MS/MS Analysis.
Fangyuan Zheng, Mingming Ding, Aidong Lu, Yueping Jia, Leping Zhang, Kaizhi Lu, Huimin Zeng
Pediatric blood & cancerOct 1, 2026PMID 42578491doi:10.1002/1545-5017.70588 Journal ArticlepubmedProvenance
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- Sep 10, 2026
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- ING-PUBMED-20260910-000001
Abstract
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We measured dasatinib concentrations in paired plasma and cerebrospinal fluid (CSF) samples from children with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Blood samples were collected from children at 0 h (pre-dasatinib) and 2 h post-dasatinib, along with CSF. After…
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