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Novel Perfluoroalkyl Substance GenX exposure promotes non-small cell lung cancer progression by regulating the OTUB1/STAT3/VEGF axis.

Hao Wang, Yang Chen, Zhao Xue, Sijia Cheng, Peipei Tian, Yu Dong, Qingjun Meng

Food and chemical toxicology : an international journal published for the British Industrial Biological Research AssociationNov 1, 2026PMID 42575423doi:10.1016/j.fct.2026.116307 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 9, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260909-000004
Published

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Lung cancer continues to be one of the deadliest malignancies worldwide, and its pathological progression is closely linked to a wide spectrum of environmental risk factors. Hexafluoropropylene oxide dimer acid (HFPO-DA), an emerging class of per- and polyfluoroalkyl substances (PFAS), has been…

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