Publication
Stemness-driven INTS7 overexpression links metabolic comorbidity to chemoresistance in acute myeloid leukemia with type 2 diabetes.
Mengxian Jin, Yue Yu, Shenyang Zhuang, Hao Ni, Zhihua Xu
Leukemia researchOct 1, 2026PMID 42574951doi:10.1016/j.leukres.2026.108290 Journal ArticlepubmedProvenance
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- Oct 1, 2026
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- ING-PUBMED-20261001-000001
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BACKGROUND: Acute myeloid leukemia (AML) often coincides with type 2 diabetes mellitus (T2D), yet the impact of metabolic comorbidity on leukaemic biology and prognosis remains underexplored. METHODS: We integrated two transcriptome-derived stemness indices (mRNAsi, EREG.mRNAsi) with weighted…
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