Publication
The G-quadruplex ligand CX-5461 inhibits laryngeal cancer via inducing immunogenic cell death and remodeling the tumor immune microenvironment.
Fang-Yuan Teng, Bo Zhang, Yue-Xi Liu, Qi Wu, Yong Xu, Gang Qin, Hong-Xia Li
International immunopharmacologyAug 10, 2026PMID 42574810doi:10.1016/j.intimp.2026.117229 Journal ArticlepubmedProvenance
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- PubMed
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- Sep 9, 2026
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- ING-PUBMED-20260909-000004
Abstract
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BACKGROUND AND OBJECTIVE: G-quadruplex (G4) structures, formed by guanine-rich nucleic acids, are implicated in tumor progression and represent promising therapeutic targets. In laryngeal cancer, the profile and clinical relevance of G4s, as well as the efficacy of G4 ligands, remain unexplored.…
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- cancerMalignant Laryngeal Neoplasmdictionary0.60
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