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Single-cell transcriptomics reveals CD8 + T-cell heterogeneity linked to immunotherapy response in gastric cancer.

Mingde Zang, Yi Xuan, Guanlin Li, Youdong Liu, Jie Chen, Jun Lu, Fenglin Liu, Hongda Pan

Biochemical and biophysical research communicationsSep 24, 2026PMID 42567001doi:10.1016/j.bbrc.2026.154385 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260929-000001
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Immune checkpoint blockade elicits durable responses in a subset of patients with gastric cancer, yet the cellular programs underlying therapeutic divergence remain unclear. Using integrative single-cell transcriptomics of tumors from Immune Checkpoint Inhibitor (ICI)-treated patients, we resolved…

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