Publication
Redox-responsive polymeric nanocarriers for targeted delivery of bruceantin to pancreatic cancer.
Yitayal Admassu Workie, Kongbrailatpam Shitaljit Sharma, Vladislav Grigoriev, Yoon Tae Goo, Prem Singh, Ana Paula Mesquita Souza, Karthickraja Duraisamy, Akshay Vyawahare, Constanze Raitmayr, Neera Yadav, Chao Wang, Olena R Taratula, Oleh Taratula
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- PubMed
- Retrieved
- Sep 14, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260914-000001
Abstract
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Bruceantin (BCT), a natural product with promising anticancer properties, has limited clinical utility due to its hydrophobicity, low systemic bioavailability, and dose-limiting toxicity. Here, we report a redox-responsive polymeric nanoplatform based on a disulfide-linked diblock copolymer,…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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