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Total Neoadjuvant Therapy for the Treatment of Locally Advanced Rectal Cancer.

Bryan Szeglin, John Migaly

Advances in surgerySep 1, 2026PMID 42556960doi:10.1016/j.yasu.2026.03.013 Journal ArticleReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 9, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260909-000004
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The treatment of locally advanced rectal cancer has been transformed over the last century. While initially treated with surgery alone, adjuvant therapy with chemotherapy and radiation became common for locally advanced disease to prevent local and distant recurrence. Several trials subsequently…

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