Publication
Paris saponin VII promotes TRIP12-mediated SOD1 degradation to synergize with idarubicin in ROS-dependent acute myeloid leukemia cell death.
Runfeng Ni, Ning Ding, Yirong Shi, Milin Liu, Jing Wang, Yuchen Tao, Jizhang Bao, Yuanfei Mao, Jiahui Lu
Phytomedicine : international journal of phytotherapy and phytopharmacologyOct 1, 2026PMID 42555990doi:10.1016/j.phymed.2026.158662 Journal ArticlepubmedProvenance
- Source
- PubMed
- Retrieved
- Oct 1, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20261001-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
BACKGROUND: Acute myeloid leukemia (AML) cells evade apoptosis through antioxidant mechanisms. Paris saponin VII (PS VII), a steroidal saponin, exhibits antitumor activity in solid malignancies, but its role in AML remains unclear. PURPOSE: This study investigated the antileukemic effects of PS VII…
Read on PubMedLinked entities
Linked entities (1)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Candidate 1
- cancerLeukemiadictionary0.60
Curated evidence
Evidence citing this paper (0)
Data not yet available
No curated evidence item cites this publication.