Publication
Endoplasmic reticulum stress promotes leukemic plasmacytoid dendritic cell differentiation skewing and immune suppression in acute myeloid leukemia.
Xingcheng Yang, Juan Peng, Xia Mao, Lei Zhang, Shaolong He, Chunyan Wang, Yicheng Zhang, Yuting Tang, Jue Wang, Jia Wei
LeukemiaOct 1, 2026PMID 42547819doi:10.1038/s41375-026-03080-4 Journal ArticlepubmedProvenance
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- Oct 1, 2026
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Mature plasmacytoid dendritic cell proliferation associated with acute myeloid leukemia (pDC-AML) is a distinct entity with poor prognosis. Yet, the mechanisms underlying the immune evasion and aberrant pDC expansion remain poorly understood. We performed multi-omic profiling of 18 pDC-AML cases,…
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