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Integrative transcriptomics and single-cell analysis identify SIX4 as a candidate epithelial target in ovarian cancer and PCOS-associated ovarian dysregulation.

Xuan Li, Gaowen Chen, Yifeng Wang, Chunfang Ha

Translational oncologyOct 1, 2026PMID 42546664doi:10.1016/j.tranon.2026.102967 PMC13448444Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20261001-000001
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PURPOSE: Ovarian cancer is a heterogeneous solid tumor, whereas polycystic ovary syndrome (PCOS) is a distinct endocrine-metabolic ovarian disorder. Whether PCOS-associated ovarian dysregulation and ovarian cancer share convergent transcriptomic candidates remains unclear. This study aimed to…

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