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Exposure-Response Analyses to Inform the Optimal Epcoritamab Monotherapy Dosing Regimen in Relapsed or Refractory Follicular Lymphoma.

Mahipal Sinnollareddy, Kinjal Sanghavi, Leonid Gibiansky, Tommy Li, Matthew Putnins, Mohamed-Eslam F Mohamed, Poliana Patah, Elena Favaro, Manish Gupta, Apurvasena Parikh, Steven Xu

Clinical pharmacokineticsSep 1, 2026PMID 42541678doi:10.1007/s40262-026-01661-1 PMC13545055Journal ArticleClinical Trial, Phase IClinical Trial, Phase IIpubmedProvenance
Source
PubMed
Retrieved
Sep 10, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260910-000001
Published

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BACKGROUND: Epcoritamab is approved for treating various relapsed/refractory (R/R) lymphomas. In a phase I/II study in R/R follicular lymphoma (FL) patients, epcoritamab demonstrated high response rates (EPCORE NHL-1: objective response rate [ORR]: 82.0%, complete response [CR] rate: 62.5% [N =…

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Validated 2

Registered trialsNCT03625037NCT04542824

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