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High-throughput UHPLC-MS/MS Assay for the Quantification of Venetoclax in Patients with Acute Myeloid Leukemia and Assessment of Clinical Application: A Short Communication.

Yuri Hatano, Ken Shiraiwa, Ryota Tanaka, Yoshio Sueshige, Yuko Murakami, Hironori Abe, Ryosuke Tatsuta, Kazuki Okuhiro, Kuniko Takano, Masao Ogata, Hiroki Itoh

Therapeutic drug monitoringOct 1, 2026PMID 42536984doi:10.1097/FTD.0000000000001514 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261001-000001
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BACKGROUND: Venetoclax is a B-cell lymphoma 2 inhibitor with breakthrough therapy designations and is used in the treatment of acute myeloid leukemia, particularly in patients ineligible for conventional cytotoxic chemotherapy. However, these drugs exhibit extensive pharmacokinetic variability…

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