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Dual-mode lateral flow immunoassay based on gold nanoparticle-fluorescent microsphere nanocomposites for sensitive CA-125 detection in ovarian cancer screening.

Jiahui Wang, Junhong Li, Rurui Zhou, Ying Han, Chuan Fan, Haidong Li, Meng Tian, Congcong Mi, Guodong Liu

Analytica chimica actaOct 1, 2026PMID 42508911doi:10.1016/j.aca.2026.345814 Journal ArticleResearch Support, Non-U.S. Gov'tpubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261001-000001
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BACKGROUND: Ovarian cancer remains a highly lethal malignancy, primarily due to the lack of rapid and reliable early screening tools. Cancer antigen 125 (CA-125) is a key serum biomarker, but conventional immunoassays are either too complex for point-of-care use or lack sufficient sensitivity.…

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