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Disruption of compartmentalized calcium signaling via inositol 1,4,5-trisphosphate receptors (ITPRs) and gap junctions in primary liver cancer.

Dawidson Assis Gomes, Tales Leonardo de Melo, Érica Emiliana da Silva Figueiredo, Vanessa Medeiros de Souza, Michele Angela Rodrigues

Cell calciumSep 1, 2026PMID 42508235doi:10.1016/j.ceca.2026.103171 Journal ArticleReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 11, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260911-000001
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Maintaining epithelial cell polarity is a crucial defense against neoplastic progression, ensuring precise spatial and temporal organization of signals. Central to this structural and functional integrity is the compartmentalization of Ca2+ signaling at both intracellular and intercellular levels.…

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