Publication
Dual targeting of PI3K and FGFR or CDK4/6 reveals synergistic responses in HPV-positive and HPV-negative oropharyngeal cancer spheroids.
Madeleine Birgersson, Monika Lukoseviciute, Ourania N Kostopoulou, Tina Dalianis
Molecular therapy. OncologySep 17, 2026PMID 42471999doi:10.1016/j.omton.2026.201283 PMC13380164Journal ArticlepubmedProvenance
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- PubMed
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- Sep 30, 2026
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- ING-PUBMED-20260930-000001
Abstract
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Human papillomavirus-positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) generally has a better prognosis than HPV-negative (HPV-) OPSCC. Still, chemoradiotherapy does not cure all patients; therefore, novel treatments are needed. In monolayers of HPV+ / - OPSCC CU-OP cell lines, we…
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- cancerMalignant Oropharyngeal Neoplasmdictionary0.60
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